Transplantation, Immunology and Inflammation (TRIO)

Research programme

Mission and objectives
The mission of TRIO is to define pathways and mechanisms of pathogenesis and tissue damage in patients suffering from disturbed immune homeostasis or infectious diseases as a basis for the rational design of novel strategies for repair and prevention. The overarching objective for all research activities within TRIO is to provide a platform for excellent research on the critical determinants for Tissue Damage and Repair. To achieve our mission and the main objective, TRIO strives to provide a top-quality research environment with excellent intellectual and technological
infrastructures.

Research Area
To tackle the central theme of Tissue Damage and Repair, TRIO encompasses the two partially overlapping conceptual research areas “Transplantation” and “Clinical and Applied Immunology”. The research teams associated with TRIO contribute differentially to these areas, depending on their particular research interests. Cooperation between the associated teams is promoted and implemented where appropriate. This has led to an attractive and dynamic research environment with the required critical mass that offers a multitude of opportunities for researchers in all possible
stages of their careers.

Transplantation
The sub-programme Transplantation is a major clinical challenge taken up by the UMCG; the ongoing activities accommodate transplantation programmes for kidney, liver, lung, heart, pancreas and small bowel, or combinations thereof. Accordingly, transplantation represents a major conceptual research theme and sub-programme in TRIO. Four topics are specifically addressed:

  • Chronic Transplant Dysfunction
  • Optimisation of donor organs
  • Evaluation of clinical transplant programmes
  • (Stem)Cell transplantation

Clinical and Applied Immunology
The subprogramme Clinical and Applied Immunology integrates research on autoimmunity, tumour immunology, inflammation and the roles of microbes in human health and disease. This provides excellent opportunities for interdisciplinary and cross-disciplinary research. The following topics are addressed:

  • Autoimmunity
  • Tumour immunology
  • Inflammation
  • Microbes in human health and disease - bacteriological research, virological research and epidemiological techniques

Contact

Programme leaders
Name: Prof.Dr. C.G.M. Kallenberg
e-mail Prof. Kallenberg

Name: Prof.Dr. J.M. van Dijl
e-mail Prof. van Dijl

Secretariat
Name: Mrs. M.H.Bugter
Phone: +31 (0)50 361 2945
e-mail Mrs. Bugter

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