Research Institute GUIDE
Research focus and strategy
GUIDE performs and stimulates translational, innovative drugoriented research on a selected number of diseases and chronic diseases in an interdisciplinary setting. Researchers at GUIDE focus mainly on:
- Lead discovery, development of new drugs, drug delivery and advanced formulation technology
- Translational research on the molecular and cellular mechanisms underlying disease (aetiology and pathophysiology) and on research related to treatment of disease, e.g. in the context of clinical trials and by using relevant animal models.
New insight into the pathophysiology of a selected number of diseases leads to the development of new drugs and/or treatment options (from bench to bed). Alternatively, patient-oriented research is structured in such a way that this leads to new pathophysiological concepts (from bed to bench). This basic phylosophy starts from the idea that new concepts for treatment of diseases are most fruitfully initiated and explored in 8 focussed research programmes by combining knowledge concerning the pathophysiology of a collection of related diseases with the knowledge concerning drugs.
Figure: Research at GUIDE covers the complete circle of innovative drug research
The research programmes within GUIDE are structured in such a way that optimal co-operation between clinical, preclinical and pharmaceutical researchers can take place: organized in multidisciplinary embedded across the University Medical Center Groningen and the University Center for Pharmacy. This is a unique approach in the Netherlands.
Contact Dr. P.G. Braun
scientific coordinator
e-mail Peter Braun
Publication Report '10